Anti-inflammatory cytokines (IL-4, IL-10, IL-13) in plasma during mesenteric infarction

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Anti-inflammatory cytokines (IL-4, IL-10, IL-13) in plasma during mesenteric infarction.

We have recently reported that excessive synthesis of proinflammatory cytokines such as interleukin-6 (IL6) and IL-8 may play a role in the pathogenesis of mesenteric infarction. IL-4, IL-10 and IL-13 are classified as anti-inflammatory cytokines because they reduce the secretion of proinflammatory cytokines by stimulated monocytes/macrophage. During several inflammatory states anti-inflammator...

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The capacity to down-regulate the production of IL-8 by LPS-activated human polymorphonuclear cells (PMN) has been demonstrated for IL-4, IL-10, and TGFbeta. We compared their relative capacities and further extended this property to IL-13. We report a great heterogeneity among individuals related to the responsiveness of PMN to the IL-4 and IL-13 inhibitory effects while their response to the ...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 1998

ISSN: 0962-9351,1466-1861

DOI: 10.1080/09629359891289